Know-how of fractionation purification LC using charged particle detectors and MS triggers.
An innovative technology that accurately separates unknown components and impurities, enhancing sample evaluation.
The Thermo Scientific Vanquish Fraction Collector (VFC) is a system that enables peak-triggered fractionation using UV, CAD, and MS detectors. With CAD and MS detection, it has become possible to fractionate and evaluate unknown components and impurities that were difficult to detect with conventional UV detection. This application note explains the features of the VFC equipped with innovative valve technology, using examples from plant extracts. It provides detailed practical know-how from parameter settings for accurate fractionation to applications on a semi-preparative scale. 【Features】 ■ Low contamination: Cleaning functions for needle and buffer loop ■ High precision fractionation: Automatic calculation of delay volume, peak-triggered fractionation ■ Excellent versatility: Diverse fractionation settings using UV, CAD, and MS detection ■ High reliability: Fractionation enabled by innovative valve technology
